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What makes Mounjaro different from semaglutide-based products is that it activates two hormone receptors at once: the GLP-1 receptor (which Ozempic and Wegovy target) and the GIP receptor (which plays a role in how the body processes fat and regulates insulin response)

Methods We systematically searched PubMed, Embase and Cochrane for randomized controlled trials (RCTs) comparing GLP-1 receptor agonists versus

as excess energy accumulates, white adipose tissue (WAT) cells undergo abnormal, hypertrophic growth, leading to poor blood supply (hypoxia), macrophage infiltration, and systemic inflammation