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TB500 (Thymosin beta4) facilitates angiogenesis by modulating actin cytoskeleton organization, promoting endothelial progenitor cell recruitment, and supporting neovascularization in myocardial infarction and cutaneous wound healing models (14,15)

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The present review summarizes the crucial role of enzymes in GSH degradation in tumors, as well as their potential as biomarkers and targets for tumor therapy and their potential directions for clinical translation in tumor therapies

15 Combating therapeutic resistance thus requires an integrative, precision-driven approach that includes novel drug combinations, adaptive treatment regimens, microenvironmental reprogramming and rational modulation of hostmicrobetumor crosstalk