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2016 Dec [cited 2018 Sep 3];12(10):185663

Finally, these studies show that metabolites, such as butyrate, can exert both immunostimulatory and immunosuppressive effects, depending on the tumour or immune cell type examined and the model system used, further highlighting the complexity of metabolite-mediated immune regulation

statistical analysis: Mahmoud Etebari and Farzaneh Kanani

If you experience any intolerable side effects such as nausea, vomiting, or dizziness when increasing your dose, it may be a sign that you need to slow down the dose increase or revert to a previous dose that worked for you