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A single B12 shot continues to deliver benefits for roughly two to four weeks, with peak effects in the first week and a gradual taper after
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For most people, taking 2 g or less per day is relatively safe and unlikely to cause serious side effects
Common side effects include: Nausea Vomiting Diarrhea Decreased appetite Headache Stomach pain Fatigue Constipation Dizziness Heartburn Bloating and gas Low blood sugar (especially with insulin or sulfonylureas) Mood changes Serious, but rare side effects may include: Severe allergic reactions Pancreatitis Gallstones Kidney problems Worsening diabetic retinopathy Heart rate changes Suicidal thoughts or behaviors Thyroid cancer Bowel obstruction This is not a complete list
