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Step 2: Match the diagnosis code to your actual BMI and conditions Insurance companies require the diagnosis code on the prior authorization to accurately reflect your current BMI category and any related health conditions

The Verdict : While both are highly effective, clinical data suggest that Mounjaro (tirzepatide) generally leads to a higher percentage of total body weight loss compared to Wegovy, likely due to its dual-hormone mechanism.Dosage and Administration The good news for patients is that both medications are relatively easy to use once you get the hang of them

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[6] Preclinical studies in animal models suggest that GLP-1 receptor activation may: Promote neuroplasticity and neurogenesis (formation of new neurons) in the hippocampus, a region often showing reduced volume in depression Modulate neurotransmitter systems , particularly dopamine and serotonin pathways involved in mood regulation and reward processing Reduce neuroinflammation , which is increasingly recognised as contributing to depressive disorders Enhance brain-derived neurotrophic factor (BDNF) expression, a protein crucial for neuronal health and resilience Metabolic improvements associated with GLP-1 therapy may also contribute indirectly to mood benefits