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It is the first medication in a class known as dual-agonists
Injectable semaglutide at equivalent therapeutic doses (2.4mg weekly Wegovy) produces average weight loss of 14.9% over 68 weeks in clinical trials
Its activity can be enhanced by altering the phospholipid composition of fat droplets and is complemented by gastric lipase's partial hydrolysis of triglycerides
Park Y, Ziegler TR, Gletsu-Miller N et al (2010) Postprandial cysteine/cystine redox potential in human plasma varies with meal content of sulfur amino acids
![examples of glp 1 analogues List current GLP-1 and its analogs [36-39] List of current GLP-1 and –](https://www.researchgate.net/publication/371322849/figure/tbl1/AS:11431281165596278@1686056417230/List-of-current-GLP-1-and-its-analogs-36-39.png)
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