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Long-term deficiency can lead to cognitive problems
MC4R activation promotes increased energy expenditure through stimulation of sympathetic nervous system activity, brown adipose tissue thermogenesis, and enhanced fatty acid oxidation
Melanotan I (afamelanotide) is sold under the brand name Scenesse and is approved in the European Union for erythropoietic protoporphyria (EPP), a condition where sunlight exposure causes severe pain
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