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NPM1 mutation occurs in a subset of Ph+ AML suggesting that this entity is distinct from CML in myeloid blast phase
Preclinical results in the literature have not been uniform
Thus further work needs to be done to clarify this issue
It is found in nearly every cell in the body, with higher concentrations in tissues such as the: Liver Lungs Brain Skin Eyes Gastrointestinal tract Glutathione plays a role in cellular processes related to antioxidant activity and maintaining internal balance
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