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Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose
doi:10.1093/aje/kww212
A refusal to give an injection even one day early can prolong a period of distress and symptomatic decline
Some people may begin noticing initial changes in energy levels within the first few weeks, while more consistent improvements may emerge between 3090 days of use
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