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This is very exciting because breast cancer is one of the obesity associated cancers and bariatric surgery, while effective to reduce breast cancer risk, is not scalable at a population level. Elizabeth McDonald, MD, PhD Additionally, estrogen blockers, while effective and necessary when recommended by a physician, have unfortunate side effects that reduce compliance and also limit their use to women at high risk of breast cancer, she added

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On a systemic level, SCFAs regulate the UCP2-AMPK-ACC metabolic network via activation of peroxisome proliferator-activated receptor gamma (PPAR), which promotes fatty acid oxidation and mitigates ROS production induced by lipid accumulation [73]

Depending on the clinicians decision, treatment may include a compounded GLP-1 or GLP-1/GIP medication