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Ondansetron, metoclopramide, prochlorperazine, and promethazine are effective for managing nausea caused by GLP-1 medications
Improvements in glycemic parameters and quality of life measures were also observed
Important safety considerations include risks of medullary thyroid carcinoma (contraindicated in patients with MEN2 or family history of MTC), pancreatitis, gallbladder disease, acute kidney injury with severe gastrointestinal adverse effects, and potential diabetic retinopathy complications in patients with type 2 diabetes
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