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Made from only 12 amino acids, it increased neuronal activity tenfold compared with controls
Results Case report A 35-year-old female with GH-secreting pituitary tumors was treated with surgery and medical therapy using the first-generation SSA, octreotide, and the D2 agonist, cabergoline
This process, known as proteolytic degradation, renders most peptide drugs ineffective when swallowed in a conventional tablet or capsule
The peptide also activates alternative angiogenic pathways including VEGF-independent routes via Src-caveolin-1-eNOS signaling, providing redundant mechanisms for vascular regeneration
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