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Its worth noting that the copper ion isnt just along for the ride

Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called the intrinsic factor

Fibromyalgia syndrome involves a constellation of symptoms, which may include chronic disseminated pain without synovitis, aches, and/or myofascial tenderness, fatigue, cognitive impairment, sleep disturbances (commonly alpha wave electroencephalographic anomaly), morning stiffness, prior disease and anxiety symptoms, impaired social occupational functioning, and sexual dysfunction

In a very practical sense, B12 and other water-soluble vitamins are the safest and easiest nutrients to supplement because your body takes what it needs and gets rid of what it doesnt