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The hypoxic state not only directly reduces the activity of certain drugs, but also activates the expression of a series of genes related to drug resistance by inducing upregulation of hypoxia-inducible factor (HIF) (Cabanos and Hata, 2021
Hormonal Regulation Preliminary Research Research demonstrates DSIP's broad effects on neuroendocrine function including modulation of growth hormone release patterns, luteinizing hormone secretion, and thyroid hormone metabolism that may contribute to its sleep-promoting and regenerative properties
Honda K, Yasuhara A, Saneyasu T, Kamisoyama H
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