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In a healthy body, when you stand up, baroreceptors (specialized nerves in your blood vessels) instantly detect the drop in blood pressure and signal your sympathetic nervous system to constrict the blood vessels, pushing blood back up to your brain
Uncommon (affects 110 in 1,000 people): itching, rash, lightheadedness, or joint pain
however, unlike nicotinic acid, niacinamide does not usually cause the intense flushing reaction (redness/itching) of the skin
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