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You should avoid this combination if you: Have liver disease or take medications processed by CYP450 enzymes Are pregnant, breastfeeding, or under 18 safety data is lacking Have a sensitive digestive system and dont tolerate GI side effects well Already take metformin or other insulin-sensitizing drugs, as stacking may be redundant or risky If any of these apply to you, consult a healthcare provider before adding berberine or consider safer, more studied alternatives

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Due to ceiling effects in EQ index scores, a two-part model was used: logistic regression for full health (index = 1) and generalised linear regression for scores 30 vs

FDA warns that SGLT2 inhibitors for diabetes may result in a serious condition of too much acid in the blood