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Small molecule drugs Currently, there are 2 small molecule drugs targeting GCGR in clinical development: PegBios GCGR -only agonist PB-722 and the Tianjin Instituteof Pharmaceutical Researchs GCGR x GLP-1R dual agonist TY-751.Bothof these drugs have had their clinical trial applications accepted for review
Cruciani RA, Zhang JJ, Manola J, Cella D, Ansari B, Fisch MJ
Changes from baseline The intake of L-carnitine did not lead to a significant difference in the fasting blood sugar, triglycerides, and high-density lipoprotein-cholesterol between the intervention and placebo groups
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