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If you experience serious side effects, it could be a reason to discontinue use

& Spanel-Borowski, K

Cu2+ binds in a square-planar geometry with four nitrogen donor atoms: the N-terminal amino nitrogen of glycine, the deprotonated backbone amide nitrogen between Gly-1 and His-2, the imidazole N(delta) nitrogen of histidine, and the deprotonated backbone amide nitrogen between His-2 and Lys-3

Tirzepatide's own dedicated cardiovascular outcomes trials (including NCT07619508 and NCT06980623) are still ongoing, so its heart-health data, while promising, is less mature than semaglutide's