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Cancer 109(6):1152-1156, 2007
A critical and unresolved translational question is whether the 0.4% CSF-to-plasma ratio achieved at clinical doses is sufficient to meaningfully engage central GLP-1 receptors and activate the neuroprotective pathways described in Section 5
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Changes in bowel movements: Some vitamins are linked to poor bowel motility, and constipation can cause stool to get stuck in the outpouchings called diverticula, leading to increased pain
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