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Traditional weight loss medications use different mechanisms to aid in weight reduction: Phentermine is believed to reduce appetite, and orlistat may reduce fat absorption by inhibiting digestive enzymes
Mol Nutr Food Res 60 , 10901098, (2016)
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Study Design Participants at 444 sites in 33 countries were randomly assigned in a 1:1 ratio to receive either once-daily oral semaglutide or matching placebo, in addition to standard care (n=4,825 for both semaglutide and placebo groups)
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