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Sarcopenia aetiology is multi-factorial, driven by progressive anabolic resistance to nutrition and physical activity [36, 37], and age-related structural (vertebral compression and unfavourable fat deposition [38]), metabolic (reduced basal metabolic rate [39]) and hormonal (lower circulating anabolic hormones (testosterone, growth hormone and insulin-like growth factor-1)) changes

Oral semaglutide for weight loss is suitable for adults who are part of a comprehensive weight management plan, including a low-calorie diet and higher physical activity

Coenzyme Q10 (CoQ10) is a well-known lipophilic free radical that traps antioxidants

This approval provides a new therapeutic option for MASH, capable of halting progression and reversing established hepatic injury