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However, a high-fat diet and subsequent development of NASH can downregulate hepatic GLP-1R expression, thereby inducing therapeutic resistance to this medication in certain patients (Svegliati-Baroni et al., 2011
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Cosmetics 2018, 5, 29
Weeks 3 to 4: Initial Weight Changes Begin As appetite suppression becomes more consistent, daily calorie intake decreases naturally without intentional restriction
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