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Although Ru II -01 showed greater affinity for DNA, in line with previous evidence, caspase-3 activation is consistent with DNA fragmentation primarily for Ru II -02 ( Free curcumin has also shown a marked antihyperglycemic effect, improving insulin sensitivity
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NRP1 structure/function NRPs are single-pass transmembrane, non-tyrosine kinase surface glycoproteins, expressed by endothelial, immune, and vascular smooth muscle cells and are regulators of numerous signaling pathways within the vasculature 313,314
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