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The results of flow cytometry also demonstrated that, as detected by Annexin staining, FOXO4-DRI treatment significantly promoted apoptosis in senescent cells (Figure 6E)
A personalized treatment plan may include: progressive strengthening exercises physiotherapy flexibility and mobility training activity modification weight management where appropriate nutritional support regenerative therapies when clinically indicated regular follow-up to monitor progress For athletes, rehabilitation may emphasize restoring strength, balance, and sport-specific movement patterns before returning to competition
A synthetic version of the FOXO4 protein is FOXO4-DRI, which was developed to be identical to a fragment of the endogenously available FOXO4 protein, except for the alteration in its amino acid structure
doi: 10.1016/S0140-6736(09)62124-3 155 WangWLoACY
