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Kinetic constants K m and V max were calculated from the double-reciprocal plot of 1/v versus the 1/[S] or Lineweaver-Burk plot in which V max = 1/y-intercept of the regression line and K m = V max slope of the regression line

Culture work consumes this material in extremely small amounts, protein solutions do not keep the way lyophilized material does, and a larger vial would mostly guarantee that most of it degraded before it was used

Targeting DNA damage response pathways in cancer

The gradual progression serves pharmacodynamic purposes beyond simple tolerability, allowing metabolic adaptations to develop fully