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Administered subcutaneously, its injectable form is rapidly absorbed and distributed to metabolically active tissues, where it specifically binds and inhibits NNMT catalytic activity without interfering with other enzymes in the nicotinamide pathway or NAD+ synthesis
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Retatrutides Phase 2 trial data showed 24.2% average weight loss at the 12 mg dose over 48 weeks
Cages were exchanged for new sanitized cages filled with irradiated bedding every 2 weeks
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