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Individuals with this genotype may benefit from prioritizing consistent sun protection (broad-spectrum SPF, protective clothing) and supporting skin health through a diet rich in antioxidants (vitamin C, vitamin E, carotenoids like beta-carotene and astaxanthin) that help counteract UV-induced oxidative stress
An EXSCEL trial showed significant changes in systemic inflammatory markers
For the latter, the reninangiotensinaldosterone system inhibitors (RAS) blockers are used, given their renoprotective efficacy beyond blood pressure lowering per se
It makes sense for both researchers and supplement companies to focus on NMN and NR, as the salvage pathway is responsible for so much NAD+ production
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