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Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

GLP-1 medications help support appetite regulation and blood sugar control to promote steady, sustainable weight management

The running buffer (PBST, 25 C) was degassed prior to use

The specific dosage and frequency are determined by the prescribing provider based on the patients clinical condition, therapeutic goals, and response to treatment