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STEP-UP trial The STEP-UP trial assessed a high dose semaglutide (7.2 mg) in patients with overweight or obesity without T2D
Mitochondrial content and function in skeletal muscle are regulated by GLP-1
This is because sustainable weight loss is associated with better health outcomes and a reduced risk of weight-related health conditions and complications
Under medical supervision, dosing is carefully adjusted to maximize effectiveness while minimizing side effects
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