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Gene Activation : It up-regulates genes related to collagen synthesis (COL1A1, COL3A1) and elastin formation, making the skin look firmer and younger
however, this may reduce peptide solubility and increase cytotoxicity
Therefore, this condition has a tendency to get worse during the winter months when there is less moisture in the air, and is more likely to occur in individuals with a history of other skin conditions that cause dryness
Delicate skin problems Some areas of the skin require special delicacy, as they are easily weakened
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