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Gas and air mix contains nitrous dioxide and this gas inactivates B12 in the body
Pernicious anemia occurs more commonly in people who already have diseases that are linked to immune-system abnormalities, such as Graves disease, hypothyroidism (under-functioning thyroid gland), thyroiditis (inflammation of the thyroid), vitiligo, and Addison's disease (adrenocortical insufficiency)
doi: 10.3322/caac.21834 3
These tend to be most pronounced during the dose escalation period and generally improve over time
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