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A randomized, placebo-controlled pilot study examined adding phentermine to liraglutide (a GLP-1 agonist similar in class to tirzepatide) in adults with obesity who had already been on liraglutide for one year and achieved approximately 12% weight loss
They bind to the same receptors in the brain and gut, but they stay active in your system much longer than the hormones your body produces on its own
However, reaching this maximum dose isn't necessary for everyone
Understanding how quickly tirzepatide produces results can also help you set realistic expectations for each titration phase
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