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Try the BMI Calculator Metabolic root cause correction: By dramatically improving insulin sensitivity and glucose metabolism, tirzepatide may address the metabolic dysfunction that feeds fibromyalgia pain circuits Dual-pathway neuroinflammation reduction: Both GIP and GLP-1 receptor activation in the brain suppress microglial activation and pro-inflammatory cytokine production, potentially quieting the central sensitization that underlies fibromyalgia pain Mitochondrial function support: Improved insulin signaling and reduced oxidative stress may improve mitochondrial energy production in muscle tissue, addressing the cellular basis of fibromyalgia fatigue Breaking the pain-weight cycle: Substantial weight loss reduces mechanical pain, improves mobility, and enables the exercise that's one of fibromyalgia's most effective treatments Sleep quality improvement: Weight loss, particularly visceral fat reduction, can improve sleep apnea and sleep architecture

It helps protect cells from damage caused by free radicals that form when oxygen is used to create energy for repair and regeneration

The honest answer is patient demand and revenue

DPP4 is a serine exopeptidase that catalyzes the release of an N-terminal dipeptide provided that the next to last residue is proline, hydroxyproline, dehydroproline or alanine