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Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells
If GLP-1 receptor agonism, and by extension the dual and triple agonists, and possibly the cleaner endogenous peptides like BRP, operates as a class of geroscience interventions rather than a class of weight-loss drugs that happen to have nice cardiovascular side benefits, then the population for whom these molecules might matter is much larger than the population that currently qualifies for them under any obesity- or diabetes-based prescribing guideline
2 2.8.3 Widely targeted metabolomics analysis Frozen tissue specimens were homogenized and extracted using ice-cold methanol:water (7:3, v/v) supplemented with isotope-labeled internal standards,followed by multi-platform LC-MS/MS analysis
