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[16] [18] Animal studies have not demonstrated teratogenicity, but high doses in pregnancy may theoretically increase the risk of fetal oxalate nephropathy or other metabolic disturbances

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Ice crystals physically shear peptide chains and create aggregated clumps that do not redissolve uniformly when thawed

While gender was tested as a covariate in all analyses, the small sample size and low percentage of enrolled females did not allow us to investigate possible gender differences in endocrine outcomes after cannabis administration