These effects are generally mild and transient, often diminishing as the body adjusts to the medication
CR was defined as the disappearance of all target lesions and PR as a 30% reduction in their total diameter
The practice is built to support patients at every phase of their journey whether they are seeking subtle refinement or a major transformation

Patients should: Stay well hydrated Eat smaller, more frequent meals Avoid high-fat, greasy, or very spicy foods if experiencing nausea Report persistent or severe symptoms to their prescriber When to seek medical advice: Contact your GP or diabetes team for: Persistent vomiting or diarrhoea Concerns about medication effects or side effects Symptoms of hypoglycaemia if taking other diabetes medications Contact NHS 111 or seek urgent care for: Severe, persistent vomiting preventing fluid intake Signs of dehydration (dark urine, dizziness, reduced urination) Severe or persistent abdominal pain, particularly if radiating to the back (potential pancreatitis) Pain in the right upper abdomen, yellowing of skin/eyes (potential gallbladder issues) Sudden vision changes Allergic reactions (rash, difficulty breathing, facial swelling) Most patients find that side effects diminish significantly after 812 weeks, and the benefits of appetite control and metabolic improvement become more apparent