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Phase 2 failed primary endpoint Attribute Unique advantage SLU-PP-332 Only pan-ERR agonist with demonstrated in-vivo exercise-mimetic activity MOTS-c Endogenous mitochondrial peptide with AMPK-focused signaling AOD-9604 Most human clinical history of the three Half-life and dose figures across the three compounds are mostly from animal data and should not be read as validated human pharmacology

This dual modulation allows BPC-157 to normalize nitric oxide levels whether they are pathologically elevated or depleted, providing adaptive vascular protection