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According to the American Cancer Society (ACS), it can have a Chemotherapy injections may cause typical injection site reaction symptoms, including: skin discoloration swelling itching tenderness warmth However, chemotherapy drugs sometimes cause a symptom known as extravasation, which is when the medication leaks from the vein and into the surrounding tissue

J Nutr 130:26262629 Wu G, Morris SM Jr (1998) Arginine metabolism: nitric oxide and beyond

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