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In HG-induced HK-2 cells, calycosin has been demonstrated to upregulate GPX4, inhibit lipid ROS, and suppress the expression of nuclear coactivator 2 (NCOA2), thereby enhancing HK-2 cell survival and mitigating cellular damage (Huang D

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doi:10.1111/j.1365-2672.2008.03892.x Liang G, Liao X, Du G, Chen J (2009) A new strategy to enhance glutathione production by multiple H2O2 induced oxidative stresses in Candida utilis

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