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A separate 2025 narrative review confirmed three total published human pilot studies and noted that no major adverse events were reported across those pilots [15]
What cannot be promised Specific weight-loss targets, body-composition changes, or joint outcomes cannot be promised based on current evidence
Mistake 2: not tracking cumulative room temperature time Many people treat the 21-day limit as a single continuous event
Headaches, nausea, diarrhea, fatigue, and tingling in extremities are very rare
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