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5-Ethynyl-2-deoxyuridine (EdU) incorporation assay DNA synthesis was assayed using the BeyoClick EdU Cell Proliferation Kit (Beyotime) according to the manufacturers instructions

The proposed mechanism involves beta-3 adrenergic receptor stimulation and enhanced fatty acid oxidation in adipocytes [6]

A head-to-head study conducted in 2016 revealed that both Trulicity and Januvia effectively managed blood glucose levels, however, patients receiving Trulicity showed a greater reduction in HbA1c (a long-term measure of blood glucose control) compared to those on Januvia

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