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Engineered exosomes called (Exo-pYSTAT3 IB) were produced using EXPLOR, these small exosomes were loaded with an mCherry-tagged intracellular antibody (intrabody, IB) targeting a Tyr705-phosphorylated signal transducer and activator of transcription 3 (pYSTAT3)
Autophagy 19 (10), 26212638
Sources and references MHRA / GOV.UK: First GLP-1 tablet for weight loss approved in the UK NHS: Overweight and obesity in adults NICE NG246: Medicines for overweight and obesity New England Journal of Medicine: Oral semaglutide 25 mg in adults with overweight or obesity European Medicines Agency: Wegovy tablets for oral use positive opinion MHRA Drug Safety Update: Semaglutide and NAION MHRA Yellow Card: report a suspected side effect MHRA / GOV.UK: GLP-1 medicines for weight loss and diabetes MHRA Products: official SmPC and patient leaflets UK prescribing decisions should follow UK regulatory information, the prescriber's clinical assessment and the official UK product information when published
It can also mean losing lean muscle mass if youre not careful
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