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The TCF7L2 Gene: Your GLP-1 Regulator The TCF7L2 gene is a GLP-1 regulator and its important because it: Directly regulates the production and secretion of GLP-1 Influences how well GLP-1 can stimulate insulin release Its strongly linked to type 2 diabetes risk (the strongest genetic risk factor identified!) When you have certain variants of TCF7L2, your body produces less GLP-1 and responds more weakly to the GLP-1 you do produce

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Note: While genetic data from services like 23andMe or AncestryDNA can provide part of the picture on medication metabolism, for a better understanding of your drug metabolism issues, your doctor may recommend getting a clinical-grade test done

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