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The 24.2% weight reduction at 48 weeks, combined with improvements in triglycerides, liver enzymes, and insulin sensitivity markers, positions Retatrutide as the more mechanistically complete compound in the Retatrutide vs Tirzepatide framework, pending Phase 3 confirmation
doi: 10.1056/NEJMoa1901118 20 PieberTRBodeBMertensAChoYMChristiansenEHertzCLet al
GWAS summary statistics for aptamers are available at Details regarding the hallmark gene set collection are provided in ref
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