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One plausible explanation is that advanced hepatic steatosis or fibrosisconditions associated with more severe insulin resistancemay attenuate the metabolic responsiveness to incretin-based therapies
Patients who have started or maintained exercise programs may notice improved endurance and changes in body composition
In briefing materials published ahead of the meeting, FDA career reviewers recommended against adding any of the seven substances, citing insufficient safety and effectiveness data
About 17% in the group that took Wegovy and about 8% of those who received placebo left the study because of those effects
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