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Bombeli T, Schwartz BR, Harlan JM
473,474,475 In MS, mitochondrial injury contributes to both neuroinflammation and neurodegeneration
COMMON USES Treatment and prevention of B12 deficiency Support for fatigue and low energy Neurological support (numbness, tingling, brain fog) Support for anemia Adjunct therapy for metabolic and weight-loss programs Support during GLP-1 or caloric restriction therapy ADMINISTRATION METHODS Vitamin B12 may be administered via: Oral supplementation Sublingual tablets or liquids Intramuscular (IM) injection Subcutaneous (SubQ) injection Injectable forms provide rapid absorption and are commonly used when deficiency or malabsorption is present
Trimetazidine is rapidly absorbed with high bioavailability, reaching peak plasma concentration of 53.6 mg/L within 1.8 h for immediate release and steady level within 24 h for modified release [112, 114]
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