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Glucokinase ( GCK ), a master regulator of glucose homeostasis that catalyzes the first and rate-limiting step of glycolysis, was one enzyme with the most reduced abundance, by nearly eightfold in UGT2B17-deficient livers (Figs
IF images were acquired using a Leica TCS-SP8 confocal microscope
Effects beyond 68 weeks are simply unstudied
By suppressing caspase activation and modifying Bcl-2 family proteins, melatonin also promotes cellular viability
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