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If the answer is no, plan your exit strategy during treatment

Kaplan says that stool softeners like Colace work by drawing water into the stool, making it softer, and are generally safe for long-term use

Contrary to pancreatic -cells, the mechanism of GLP-1 stimulation-secretion coupling in intestinal L-cells is poorly understood 32

In fact, the absorption of B12 requires that you have adequate stomach acid (among many other factors), which means that if you are taking acid blockers for reflux you are likely reducing your absorption of B12