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Beyond BMI criteria, ideal candidates are patients who have attempted lifestyle modifications (diet, exercise) without achieving adequate or sustained weight loss
Continued response = switching is optional and preference-driven
Exercise Log Data Participants were asked to complete a log of all resistance training exercise performed during the week prior to initial testing and last week of the four week study
Given the clear relationship between IGF-1 and aging, we reasoned that IGF-1R mAbs could provide a translational tool to mimic the beneficial effects reported by reduced signaling in this pathway
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