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Use of MOUNJARO for this indication is supported by a 30-week, randomized, double-blind, placebo-controlled trial with a 22-week open label extension in 99 pediatric patients [see Clinical Studies ( 14.5 )]
Deletion sequences (missing amino acids), racemization (wrong chirality), and oxidation products can occur without proper controls
Phase 01
However, for those with a BMI 40 or BMI 35 with obesity-related comorbidities, GLP-1 agonists alone often do not provide the degree of weight loss required for disease control or resolution
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